With regard to the implementation of the agreement, developed countries had one year to bring their laws and practices into line with the agreement. This period has been extended to five years for developing and countries that have moved from a centralized economy to a market economy, and to 11 years for the least developed countries. The Agreement on Trade-Related Intellectual Property Rights (TRIPS) is an agreement of international law between all World Trade Organization (WTO) member states. It sets minimum standards for the regulation of different forms of intellectual property by national governments, as is the case for nationals of other WTO member states.  The TRIPS agreement was negotiated at the end of the Uruguay Round of the General Agreement on Tariffs and Trade (GATT) between 1989 and 1990 and is managed by the WTO. The General Council assigns responsibility to three other important bodies: the councils for trade in goods, trade in services and the ADPIC Council. The Goods Council oversees the implementation and operation of all merchandise trade agreements, although many of these agreements have their own specific supervisory authorities. There is, for example, an agriculture commission. In the first phase of accession procedures, the applicant government is required to submit to the WTO a memorandum covering all aspects of its trade and economic policy that are important to WTO agreements. This will be the basis for an in-depth review within a working group. The 2002 Doha Declaration confirmed that the TRIPS agreement should not prevent members from taking the necessary steps to protect public health. Despite this recognition, less developed countries have argued that flexible TRIPS provisions, such as mandatory licensing, are almost impossible to obtain. The least developed countries, in particular, have made their young domestic manufacturing and technological industries proof of the infallible policy.
In short, the WTO is the common institutional framework for the implementation of trade relations between its members in the areas related to the agreements contained in the final act. Decision 94/800/EC on the conclusion, on behalf of the EU, of the agreements reached in the framework of the multilateral negotiations of the Uruguay Round (1986-1994). The Uruguay Round was the eighth round of multilateral trade negotiations (NTMs) under the General Agreement on Tariffs and Trade (GATT), which runs from 1986 to 1993 and brings together 123 countries as “contracting parties”. The cycle culminated in the creation of the World Trade Organization, with GATT remaining an integral part of the WTO agreements. The broad mandate of the round was to extend GATT trade rules to areas that were previously too liberalised (agriculture, textiles) and new and increasingly important areas that had not yet been taken into account (trade in services, intellectual property, distortion of investment policy).  The cycle came into force in 1995 and the deadlines expired in 2000 (2004 for contracting parties in developing countries) under the administrative direction of the newly created World Trade Organization (WTO).  In the short term, the WTO remains the “shell” on which previous GATT agreements are based, but it will more than likely appear in the coming years with its own organizational niche in the multilateral trading system. The Organization`s effect could be to ensure that it is behind in future trade negotiations and that it will maintain the forward momentum of the multilateral trading system. Unlike other IP agreements, TRIPS have an effective enforcement mechanism.